Ethnobotany, medicinal utilization and analysis of biogenic elements and flavonoids of Apium graveolens and Tussilago farfara from Uzbekistan

Background: Plants are a rich source of both organic and inorganic substances that play crucial role in determining their therapeutic effects. Within each medicinal plant, diverse array chemical compounds trace elements can be found, contributing to its wide spectrum healing properties. It is important highlight certain element found plants essential for sustaining life processes. Elements such as calcium (Ca), potassium (K), sodium (Na), sulfur (S), iron (Fe), silicon (Si), manganese (Mn), magnesium (Mg), zinc (Zn) involved nearly all biochemical processes within the body. They roles regulating energy metabolism, primary secondary well hormonal regulation occurring cells. This article examines ethnobotany, utilization analysis biogenic flavonoids Apium graveolens Tussilago farfara from Uzbekistan. Methods: The determination food products has been carried out using plasma inductively coupled mass spectrometry method (ICP-MS). reagents employed process included Standard No. 3, which contains multiple (29 spectrometry). Additionally, standards encompassed mercury, nitric acid, hydrogen peroxide, bi-distilled water, argon gas (with purity 99.995%). samples were subjected Agilent-1200 HPLC with diode detector, operating isocratic elution mode. mobile phase consisted mixture acetonitrile buffer solution ratio 70:30. eluent flowed at volumetric flow rate -1.0 ml/min, 10 µl sample was injected. Detection performed wavelength 254 nm. chromatographic column used Eclipse XDB-C18, dimensions 5.0 microns 4.6×250 mm. thermostat temperature maintained 300°C. Results: Analyzing study results we observed contained more than 18 elements: Highest concentration Sodium, Magnesium, Potassium, Calcium, Iron, Copper, Zinc seeds graveolens, followed by A. leaves. As result conducted on extracts six phenolic flavonoid successfully isolated. One particular flavonoid, apigenin, exhibits retention time shift during analysis, indicating presence. relatively high concentrations rutin, quercetin, dihydroquercetin further contribute significance studying these plants. Conclusion: studies focused nutrients present graveolens. calcium, magnesium, potassium, iron. Building upon findings, proposal made develop novel dietary supplements aimed providing relief treatment bone-related disorders, cardiovascular issues, anemia. Key words: celery, coltsfoot, utilization, elements, flavonoids.